Viagra Mechanism

Before to know viagra mechanism, you should know erectile function in men.
Part of the physiological process of erection involves the parasympathetic nervous system causing the release of nitric oxide (NO) in the corpus
cavernosum of the penis. NO binds to the receptors of the enzyme guanylate cyclase which results in increased levels of cyclic guanosine
monophosphate (cGMP), leading to smooth muscle relaxation (vasodilation) in the corpus cavernosum, resulting in increased inflow of blood and an
erection.


Penile erection is an important attribute during sexual intercourse. Erection of a male penis comes because of the pressure of the blood that flows
into the penis, making it engorged with blood and thus giving it some extra length and firmness. Erection can be possible when a man is awake as
well as when he is asleep. When a man dreams in his sleep during his REM (rapid eye movement) pattern of sleep, he gets penile erections even then
too.

For a better sexaual healthy relationship, successful vaginal penetration a man needs to have an erect penis. Erection comes through sexual
stimulation. For some men this may not be the case. They may not be able to achieve erections in spite of getting sexually aroused by their
respective partners. And here Viagra helps you.

Viagra provides penile erection by increasing the blood flow into the male genital region. But with Viagra you need to be sexually aroused or
stimulated to achieve the erection. Viagra will not start working on its own. Viagra is not an aphrodisiac or a hormone. Just by popping a Viagra pill
you can not assume to achieve erection.


Viagra belongs to the class of PDE5 inhibitor drugs which inhibit or block the chemicals known as phospho diesterase inhibitor drugs. The physiology
of erections involves many chemical reactions in the body. The sexual stimulation releases nitric oxide in the corpus cavernosum, the two parallel
channels situated at the sides along the length of the penis. The release of nitric oxide activates the enzyme guanylate cyclase which results in the
increased levels of cyclic guanosine monophosphate responsible for the penile erections.

Viagra works by inhibiting the chemical phosphodiesterase type 5 which is responsible for the erections turning flaccid. This prolongs the effect of
the muscle relaxation in the corpus cavernosum area of the penis allowing the blood to flow into the spongy tissues of the penis causing an erection.
Viagra does not have any direct relaxant effect on the corpus cavernosum area in the human penis but enhances the effect of nitric oxide (NO) by
inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP or cyclic guanosine monophosphate in the corpus
cavernosum. When sexual stimulation causes local release of nitric oxide the inhibition of PDE5 by Viagra causes
increased levels of cGMP or cyclic guanosine monophosphate in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to
the corpus cavernosum resulting in the required erections of the penis.