Viagra Information -
Viagra is the first
drug used for treating erectile dysfunction for man, a product
of Pfizer company. Viagra is an oral therapy for erectile dysfunction
in man, and its chemical composition is the citrate salt of
sildenafil, a selective inhibitor of cyclic guanosine monophosphate
(cGMP) a specific phosphodiesterase type 5 (PDE5).
Viagra is the
one of the best drug used for treating erectile dysfunctions.
Viagra is an oral therapy drug for ED(impotence) problems.
It's chemical formula contains citrate salt of sildenafil, a
selective inhibitor of cyclic guanosine monophosphate (cGMP) a
specific phosphodiesterase
type 5 (PDE5).
Viagra pills are blue and diamond-shaped with the words "Pfizer"
on one side, and "VGR xx" (where xx stands for "25", "50" or
"100", the dose of that
pill in milligrams) on the other.
Viagra is also informally known as "Vitamin V", "the Blue Pill",
as well as various other nicknames.
The drug was patented in 1996, approved for use in erectile
dysfunction by the Food and Drug Administration on March 27,
1998, becoming the first
pill approved to treat erectile dysfunction in the United
States, and offered for sale in the United States later that
year.
Sildenafil (compound UK-92,480) was synthesized by a group of
pharmaceutical chemists working at Pfizer's Sandwich, Kent
research facility. It was
initially studied for use in hypertension (high blood pressure)
and angina pectoris (a form of ischaemic cardiovascular
disease).
IUPAC Name -
1-[4-ethoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenylsulfonyl]-4-methylpiperazine
Viagra is used to treat impotence in men and not for women.
Viagra increases the body's ability to achieve and maintain
an erection( for those having ED problem) during sexual stimulation.
Viagra does not protect you from getting sexually transmitted
diseases, including HIV and others.
Sildenafil citrate is a white crystalline powder with a solubility
of 3.5 mg/mL in water and a molecular weight of 666.7. Viagra
(sildenafil citrate) is blue, film-coated rounded-diamond-shaped
tablets equivalent to 25 mg, 50 mg and 100 mg of sildenafil
for oral therapy. Besides to the active ingredient, sildenafil
citrate, each tablet contains the following inactive ingredients:
microcrystalline cellulose, anhydrous dibasic calcium phosphate,
croscarmellose sodium, magnesium stearate, hydroxypropyl methylcellulose,
titanium dioxide, lactose, triacetin, and FD & C Blue #2
aluminum lake.
Did you Know?
Around 28 million men in the US alone suffer from clinical
erectile dysfunction (ED) .
Viagra helps most men with erectile dysfunction achieve &
maintain erection during sex
Viagra works in as little as 14 minutes.
Viagra has a proven safety record.
Viagra is the best selling pill for erectile dysfunction in
the entire world.
Viagra is approved by FDA.
Viagra works for infact most of the men with erectile dysfunction.
The main chemical ingredient for Viagra is sildenafil citrate
which has the chemical powers to treat erectile dysfunction
in men by increasing the blood flow to the penile tissues, and
thus causing erection.
Viagra belongs to the class of PDE5 or phosphodiesterase inhibitor
drugs. cGMP is a kind of chemical composition that helps in
achieving and maintaining erection and the moment the chemical
PDE5 is released the erection goes flaccid and for a long time.
Hence the longer the onset of the chemical PDE5 can be delayed
the longer would a man continue to enjoy erections. Hence Viagra
works by inhibiting that chemical which causes the erections
to go flaccid.
History of Viagra: Sildenafil, earlier known as compound UK-92,480,
was initially developed to treat angina pectoris (a form of
cardiovascular disease). In phase I during the clinical trials,
the drug hardly showed any effects on angina; instead it had
an interesting result. The compound showed marked improvements
in the erectile problems of men. Thus the makers of Viagra decided
to market the drug as an anti-impotence drug to treat erectile
dysfunction rather than for angina.
The word ‘Viagra’ was the invention of the manufacturers
of this drug known as Pfizer. It's sound looks like the Sanskrit
word ‘vyaghra’ meaning tiger. Tiger known for strength,
power and virility. Another word related to ‘Viagra’
is the ‘Niagra Falls’ which is a popular destination
for honeymoon, where couples enjoyed and the word ‘Niagra’
also shows the feeling of vigor and virility and hence may be
the name, Viagra.
Viagra was patented in 1996 for use in erectile dysfunction
and was approved by the FDA on March 27, 1998, making the drug
Viagra as the first oral pill to treat erectile dysfunction.
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